As someone who lives in upstate NY, people pronounce Iroquois like i-ruh-KOI as it's been anglicized. The first time I heard interjection say i-ro-KWA it sounded a noticeably "off" to me but I wouldn't say it sounded "wrong" either. If you go full throated French 'r' or 'qu' on s...

looking for someone to run an xpmod game with me. message me on ESO if you want.